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A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease

BACKGROUND: Clinical failures singularly targeting amyloid-β pathology indicate a critical need for alternative Alzheimer’s disease (AD) therapeutic strategies. The mixed pathology reported in a large population of AD patients demands a multifunctional drug approach. Since activation of cAMP respons...

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Detalles Bibliográficos
Autores principales:	Luo, Jia, Lee, Sue H., VandeVrede, Lawren, Qin, Zhihui, Ben Aissa, Manel, Larson, John, Teich, Andrew F., Arancio, Ottavio, D’Souza, Yohan, Elharram, Ahmed, Koster, Kevin, Tai, Leon M., LaDu, Mary Jo, Bennett, Brian M., Thatcher, Gregory R. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850651/ https://www.ncbi.nlm.nih.gov/pubmed/27129593 http://dx.doi.org/10.1186/s13024-016-0103-6

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