Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects

BACKGROUND: Reelin plays a pivotal role in neurodevelopment and in post-natal synaptic plasticity and has been implicated in the pathogenesis of autism spectrum disorder (ASD). The reelin (RELN) gene expression is significantly decreased in ASD, both in the brain and peripherally. Methylation at the...

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Detalles Bibliográficos
Autores principales: Lintas, Carla, Sacco, Roberto, Persico, Antonio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850686/
https://www.ncbi.nlm.nih.gov/pubmed/27134686
http://dx.doi.org/10.1186/s11689-016-9151-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850686/
https://www.ncbi.nlm.nih.gov/pubmed/27134686
http://dx.doi.org/10.1186/s11689-016-9151-z

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