Cargando…
Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects
BACKGROUND: Reelin plays a pivotal role in neurodevelopment and in post-natal synaptic plasticity and has been implicated in the pathogenesis of autism spectrum disorder (ASD). The reelin (RELN) gene expression is significantly decreased in ASD, both in the brain and peripherally. Methylation at the...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850686/ https://www.ncbi.nlm.nih.gov/pubmed/27134686 http://dx.doi.org/10.1186/s11689-016-9151-z |