Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells

BACKGROUND: Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for matrix metalloproteinase 9 (MMP-9) in kidney fibrosis via induction of epithelial-mesenchymal transition (EMT). Inhibition of MMP-...

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Detalles Bibliográficos
Autores principales: Zhao, Ye, Qiao, Xi, Wang, Lihua, Tan, Tian Kui, Zhao, Hong, Zhang, Yun, Zhang, Jianlin, Rao, Padmashree, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W. S., Alexander, Stephen I., Harris, David C. H., Zheng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850690/
https://www.ncbi.nlm.nih.gov/pubmed/27130612
http://dx.doi.org/10.1186/s12860-016-0101-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850690/
https://www.ncbi.nlm.nih.gov/pubmed/27130612
http://dx.doi.org/10.1186/s12860-016-0101-0

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