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A continuum model of transcriptional bursting

Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and permissive states. Here we investigate bursting mechanism in live cells by quantitative imaging of actin gene transcription, combined with molecu...

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Detalles Bibliográficos
Autores principales:	Corrigan, Adam M, Tunnacliffe, Edward, Cannon, Danielle, Chubb, Jonathan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850746/ https://www.ncbi.nlm.nih.gov/pubmed/26896676 http://dx.doi.org/10.7554/eLife.13051

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