Myeloid neoplasm demonstrating a STAT5B-RARA rearrangement and genetic alterations associated with all-trans retinoic acid resistance identified by a custom next-generation sequencing assay

We describe the case of a patient presenting with several weeks of symptoms related to pancytopenia associated with a maturation arrest at the late promyelocyte/early myelocyte stage of granulocyte differentiation. A diagnosis of acute promyelocytic leukemia was considered, but the morphologic featu...

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Detalles Bibliográficos
Autores principales: Kluk, Michael J., Abo, Ryan P., Brown, Ronald D., Kuo, Frank C., Dal Cin, Paola, Pozdnyakova, Olga, Morgan, Elizabeth A., Lindeman, Neal I., DeAngelo, Daniel J., Aster, Jon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850893/
https://www.ncbi.nlm.nih.gov/pubmed/27148563
http://dx.doi.org/10.1101/mcs.a000307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850893/
https://www.ncbi.nlm.nih.gov/pubmed/27148563
http://dx.doi.org/10.1101/mcs.a000307

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