Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women

OBJECTIVES: DNA methylation analysis of cancer-related genes is a promising tool for HPV-positive women to identify those with cervical (pre)cancer (CIN3+) in need of treatment. However, clinical performance of methylation markers can be influenced by the sample type utilized. We describe a multiple...

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Detalles Bibliográficos
Autores principales: De Strooper, Lise M.A., Verhoef, Viola M.J., Berkhof, Johannes, Hesselink, Albertus T., de Bruin, Helena M.E., van Kemenade, Folkert J., Bosgraaf, Remko P., Bekkers, Ruud L.M., Massuger, Leon F.A.G., Melchers, Willem J.G., Steenbergen, Renske D.M., Snijders, Peter J.F., Meijer, Chris J.L.M., Heideman, Daniëlle A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851217/
https://www.ncbi.nlm.nih.gov/pubmed/26921784
http://dx.doi.org/10.1016/j.ygyno.2016.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851217/
https://www.ncbi.nlm.nih.gov/pubmed/26921784
http://dx.doi.org/10.1016/j.ygyno.2016.02.012

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