Potential Applications of Using 68Ga–Evans Blue PET/CT in the Evaluation of Lymphatic Disorder: Preliminary Observations

PURPOSE: Potentials of (68)Ga-NEB as a PET tracer in the evaluation of a variety of lymphatic drainage disorders were analyzed. METHODS: (68)Ga-NEB was injected subcutaneously, and the PET/CT images were acquired in 13 patients with different suspected lymphatic drainage abnormality. The (68)Ga-NEB...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Wu, Peilin, Li, Fang, Tong, Guansheng, Chen, Xiaoyuan, Zhu, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851227/
https://www.ncbi.nlm.nih.gov/pubmed/26859218
http://dx.doi.org/10.1097/RLU.0000000000001171
Descripción
Sumario:PURPOSE: Potentials of (68)Ga-NEB as a PET tracer in the evaluation of a variety of lymphatic drainage disorders were analyzed. METHODS: (68)Ga-NEB was injected subcutaneously, and the PET/CT images were acquired in 13 patients with different suspected lymphatic drainage abnormality. The (68)Ga-NEB PET/CT findings were compared with (99m)Tc-SC lymphoscintigraphy. RESULTS: (68)Ga-NEB activity could be clearly observed in the lymphatic route on the PET/CT images from all the patients. In 5 (38.5%) of 13 patients tested, (68)Ga-NEB PET/CT provided more information than the (99m)Tc-SC lymphoscintigraphy. CONCLUSIONS: (68)Ga-NEB PET/CT can be used as an alternative of (99m)Tc-SC lymphoscintigraphy in the evaluation of lymphatic disorders, which enables fast results and might be more accurate than the conventional (99m)Tc-SC lymphoscintigraphy.

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