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Candidalysin is a fungal peptide toxin critical for mucosal infection

Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host immune responses. Until now human pathogenic fungi were not known to possess such toxins. Here we identify the fi...

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Detalles Bibliográficos
Autores principales:	Moyes, David L., Wilson, Duncan, Richardson, Jonathan P., Mogavero, Selene, Tang, Shirley X., Wernecke, Julia, Höfs, Sarah, Gratacap, Remi L., Robbins, Jon, Runglall, Manohursingh, Murciano, Celia, Blagojevic, Mariana, Thavaraj, Selvam, Förster, Toni M., Hebecker, Betty, Kasper, Lydia, Vizcay, Gema, Iancu, Simona I., Kichik, Nessim, Häder, Antje, Kurzai, Oliver, Luo, Ting, Krüger, Thomas, Kniemeyer, Olaf, Cota, Ernesto, Bader, Oliver, Wheeler, Robert T., Gutsmann, Thomas, Hube, Bernhard, Naglik, Julian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851236/ https://www.ncbi.nlm.nih.gov/pubmed/27027296 http://dx.doi.org/10.1038/nature17625

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