Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease

Previous work has shown that the gene DMBT1, which encodes a large secreted epithelial glycoprotein known as salivary agglutinin, gp340, hensin or muclin, is an innate immune defence protein that binds bacteria. A deletion variant of DMBT1 has been previously associated with Crohn's disease, an...

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Detalles Bibliográficos
Autores principales: Polley, Shamik, Prescott, Natalie, Nimmo, Elaine, Veal, Colin, Vind, Ida, Munkholm, Pia, Fode, Peder, Mansfield, John, Skyt Andersen, Paal, Satsangi, Jack, G Mathew, Christopher, Hollox, Edward J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851238/
https://www.ncbi.nlm.nih.gov/pubmed/26813944
http://dx.doi.org/10.1038/ejhg.2015.280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851238/
https://www.ncbi.nlm.nih.gov/pubmed/26813944
http://dx.doi.org/10.1038/ejhg.2015.280

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