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A novel role for synaptic acetylcholinesterase as an apoptotic deoxyribonuclease
In addition to terminating neurotransmission by hydrolyzing acetylcholine, synaptic acetylcholinesterase (AChE(S)) has been found to have a pro-apoptotic role. However, the underlying mechanism has rarely been investigated. Here, we report a nuclear translocation-dependent role for AChE(S) as an apo...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851313/ https://www.ncbi.nlm.nih.gov/pubmed/27462404 http://dx.doi.org/10.1038/celldisc.2015.2 |