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A Plasmodium Promiscuous T Cell Epitope Delivered within the Ad5 Hexon Protein Enhances the Protective Efficacy of a Protein Based Malaria Vaccine

A malaria vaccine is a public health priority. In order to produce an effective vaccine, a multistage approach targeting both the blood and the liver stage infection is desirable. The vaccine candidates also need to induce balanced immune responses including antibodies, CD4+ and CD8+ T cells. Protei...

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Detalles Bibliográficos
Autores principales: Fonseca, Jairo Andres, Cabrera-Mora, Monica, Kashentseva, Elena A., Villegas, John Paul, Fernandez, Alejandra, Van Pelt, Amelia, Dmitriev, Igor P., Curiel, David T., Moreno, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851317/
https://www.ncbi.nlm.nih.gov/pubmed/27128437
http://dx.doi.org/10.1371/journal.pone.0154819