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A Plasmodium Promiscuous T Cell Epitope Delivered within the Ad5 Hexon Protein Enhances the Protective Efficacy of a Protein Based Malaria Vaccine
A malaria vaccine is a public health priority. In order to produce an effective vaccine, a multistage approach targeting both the blood and the liver stage infection is desirable. The vaccine candidates also need to induce balanced immune responses including antibodies, CD4+ and CD8+ T cells. Protei...
Autores principales: | Fonseca, Jairo Andres, Cabrera-Mora, Monica, Kashentseva, Elena A., Villegas, John Paul, Fernandez, Alejandra, Van Pelt, Amelia, Dmitriev, Igor P., Curiel, David T., Moreno, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851317/ https://www.ncbi.nlm.nih.gov/pubmed/27128437 http://dx.doi.org/10.1371/journal.pone.0154819 |
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