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Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer

INTRODUCTION: Buruli ulcer (BU) is a severe necrotizing human skin disease caused by Mycobacterium ulcerans. Clinically, presentation is a sum of these diverse pathogenic hits subjected to critical immune-regulatory mechanisms. Among them, autophagy has been demonstrated as a cellular process of cri...

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Detalles Bibliográficos
Autores principales: Capela, Carlos, Dossou, Ange Dodji, Silva-Gomes, Rita, Sopoh, Ghislain Emmanuel, Makoutode, Michel, Menino, João Filipe, Fraga, Alexandra Gabriel, Cunha, Cristina, Carvalho, Agostinho, Rodrigues, Fernando, Pedrosa, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851401/
https://www.ncbi.nlm.nih.gov/pubmed/27128681
http://dx.doi.org/10.1371/journal.pntd.0004671