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Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer
INTRODUCTION: Buruli ulcer (BU) is a severe necrotizing human skin disease caused by Mycobacterium ulcerans. Clinically, presentation is a sum of these diverse pathogenic hits subjected to critical immune-regulatory mechanisms. Among them, autophagy has been demonstrated as a cellular process of cri...
Autores principales: | Capela, Carlos, Dossou, Ange Dodji, Silva-Gomes, Rita, Sopoh, Ghislain Emmanuel, Makoutode, Michel, Menino, João Filipe, Fraga, Alexandra Gabriel, Cunha, Cristina, Carvalho, Agostinho, Rodrigues, Fernando, Pedrosa, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851401/ https://www.ncbi.nlm.nih.gov/pubmed/27128681 http://dx.doi.org/10.1371/journal.pntd.0004671 |
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