Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A

Bromodomain and extra-terminal (BET) family of proteins are one of the major readers of epigenetic marks and an important target class in oncology and other disease areas. The importance of the BET family of proteins is manifested by the explosion in the number of inhibitors against these targets th...

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Detalles Bibliográficos
Autores principales: Williams, Felix P., Milbradt, Alexander G., Embrey, Kevin J., Bobby, Romel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851411/
https://www.ncbi.nlm.nih.gov/pubmed/27128490
http://dx.doi.org/10.1371/journal.pone.0154607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851411/
https://www.ncbi.nlm.nih.gov/pubmed/27128490
http://dx.doi.org/10.1371/journal.pone.0154607

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