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Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A
Bromodomain and extra-terminal (BET) family of proteins are one of the major readers of epigenetic marks and an important target class in oncology and other disease areas. The importance of the BET family of proteins is manifested by the explosion in the number of inhibitors against these targets th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851411/ https://www.ncbi.nlm.nih.gov/pubmed/27128490 http://dx.doi.org/10.1371/journal.pone.0154607 |