Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to developing a malaria vaccine is the use of proteins located on the sporozoite surface as antigens to elicit...

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Detalles Bibliográficos
Autores principales: Swearingen, Kristian E., Lindner, Scott E., Shi, Lirong, Shears, Melanie J., Harupa, Anke, Hopp, Christine S., Vaughan, Ashley M., Springer, Timothy A., Moritz, Robert L., Kappe, Stefan H. I., Sinnis, Photini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851412/
https://www.ncbi.nlm.nih.gov/pubmed/27128092
http://dx.doi.org/10.1371/journal.ppat.1005606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851412/
https://www.ncbi.nlm.nih.gov/pubmed/27128092
http://dx.doi.org/10.1371/journal.ppat.1005606

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