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Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics
Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to developing a malaria vaccine is the use of proteins located on the sporozoite surface as antigens to elicit...
Autores principales: | Swearingen, Kristian E., Lindner, Scott E., Shi, Lirong, Shears, Melanie J., Harupa, Anke, Hopp, Christine S., Vaughan, Ashley M., Springer, Timothy A., Moritz, Robert L., Kappe, Stefan H. I., Sinnis, Photini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851412/ https://www.ncbi.nlm.nih.gov/pubmed/27128092 http://dx.doi.org/10.1371/journal.ppat.1005606 |
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