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Immune Defense in Upper Airways: A Single-Cell Study of Pathogen-Specific Plasmablasts and Their Migratory Potentials in Acute Sinusitis and Tonsillitis
BACKGROUND: Despite the high frequency of upper respiratory tract (URT) infections and use of the nasal mucosa as route for vaccination, the local immune mechanism and dissemination of effector lymphocytes from the URT have been insufficiently characterized. To devise a single-cell approach for stud...
Autores principales: | Palkola, Nina V., Blomgren, Karin, Pakkanen, Sari H., Puohiniemi, Ritvaleena, Kantele, Jussi M., Kantele, Anu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851416/ https://www.ncbi.nlm.nih.gov/pubmed/27128095 http://dx.doi.org/10.1371/journal.pone.0154594 |
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