Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections

Type I (IFN-α/β) and type III (IFN-λ) interferons (IFNs) exert shared antiviral activities through distinct receptors. However, their relative importance for antiviral protection of different organ systems against specific viruses remains to be fully explored. We used mouse strains deficient in type...

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Detalles Bibliográficos
Autores principales: Lin, Jian-Da, Feng, Ningguo, Sen, Adrish, Balan, Murugabaskar, Tseng, Hsiang-Chi, McElrath, Constance, Smirnov, Sergey V., Peng, Jianya, Yasukawa, Linda L., Durbin, Russell K., Durbin, Joan E., Greenberg, Harry B., Kotenko, Sergei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851417/
https://www.ncbi.nlm.nih.gov/pubmed/27128797
http://dx.doi.org/10.1371/journal.ppat.1005600

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