Serotonin Receptor 2B Mediates Mechanical Hyperalgesia by Regulating Transient Receptor Potential Vanilloid 1

Serotonin [5-hydroxytryptamine (5-HT)], an inflammatory mediator, contributes to inflammatory pain. The presence of multiple 5-HT subtype receptors on peripheral and central nociceptors complicates the role of 5-HT in pain. Previously, we found that 5-HT(2B/2C) antagonist could block 5-HT-induced me...

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Detalles Bibliográficos
Autores principales: Su, Yeu-Shiuan, Chiu, Yuan-Yi, Lin, Shih-Yuan, Chen, Chih-Cheng, Sun, Wei-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851684/
https://www.ncbi.nlm.nih.gov/pubmed/26635025
http://dx.doi.org/10.1007/s12031-015-0693-4

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