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A humanized anti-CD26 monoclonal antibody inhibits cell growth of malignant mesothelioma via retarded G2/M cell cycle transition
BACKGROUND: Malignant Mesothelioma (MM) is a highly aggressive tumor with poor prognosis. Multimodal treatments and novel molecular targeted therapies against MM are in high demand in order treat this disease effectively. We have developed a humanized monoclonal antibody YS110 against CD26 expressed...
Autores principales: | Hayashi, Mutsumi, Madokoro, Hiroko, Yamada, Koji, Nishida, Hiroko, Morimoto, Chikao, Sakamoto, Michiie, Yamada, Taketo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851800/ https://www.ncbi.nlm.nih.gov/pubmed/27134571 http://dx.doi.org/10.1186/s12935-016-0310-9 |
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