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Neuron-immune mechanisms contribute to pain in early stages of arthritis

BACKGROUND: Rheumatoid arthritis (RA) patients frequently show weak correlations between the magnitude of pain and inflammation suggesting that mechanisms other than overt peripheral inflammation contribute to pain in RA. We assessed changes in microglial reactivity and spinal excitability and their...

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Detalles Bibliográficos
Autores principales: Nieto, Francisco R., Clark, Anna K., Grist, John, Hathway, Gareth J., Chapman, Victoria, Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851814/
https://www.ncbi.nlm.nih.gov/pubmed/27130316
http://dx.doi.org/10.1186/s12974-016-0556-0

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