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Regulation of chaperone binding and nucleosome dynamics by key residues within the globular domain of histone H3

BACKGROUND: Nucleosomes have an important role in modulating access of DNA by regulatory factors. The role specific histone residues have in this process has been shown to be an important mechanism of transcription regulation. Previously, we identified eight amino acids in histones H3 and H4 that ar...

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Detalles Bibliográficos
Autores principales: Hainer, Sarah J., Martens, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851828/
https://www.ncbi.nlm.nih.gov/pubmed/27134679
http://dx.doi.org/10.1186/s13072-016-0066-4