Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy

PURPOSE: Heparanase cleaves heparan sulfate side chains of heparan sulfate proteoglycans, activity that is implicated in angiogenesis. Proteolytic cleavage of proheparanase by cathepsin L leads to the formation of catalytically active heparanase. We investigated the expression levels of heparanase e...

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Detalles Bibliográficos
Autores principales: Abu El-Asrar, Ahmed M., Siddiquei, Mohammad Mairaj, Nawaz, Mohd Imtiaz, De Hertogh, Gert, Mohammad, Ghulam, Alam, Kaiser, Mousa, Ahmed, Opdenakker, Ghislain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851855/
https://www.ncbi.nlm.nih.gov/pubmed/27168718

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