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The insulin receptor substrate Chico regulates antibacterial immune function in Drosophila
BACKGROUND: Molecular and genetic studies in model organisms have recently revealed a dynamic interplay between immunity and ageing mechanisms. In the fruit fly Drosophila melanogaster, inhibition of the insulin/insulin-like growth factor signaling pathway prolongs lifespan, and mutations in the ins...
Autores principales: | McCormack, Sarah, Yadav, Shruti, Shokal, Upasana, Kenney, Eric, Cooper, Dustin, Eleftherianos, Ioannis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852101/ https://www.ncbi.nlm.nih.gov/pubmed/27134635 http://dx.doi.org/10.1186/s12979-016-0072-1 |
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