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Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+

The objective of this study was to evaluate the present conventional selection program of a swine nucleus farm and compare it with a new selection strategy employing genomic enhanced breeding value (GEBV) as the selection criteria. The ZPLAN+ software was employed to calculate and compare the geneti...

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Autores principales: Lopez, B. M., Kang, H. S., Kim, T. H., Viterbo, V. S., Kim, H. S., Na, C. S., Seo, K. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852224/
https://www.ncbi.nlm.nih.gov/pubmed/26954222
http://dx.doi.org/10.5713/ajas.15.0842
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author Lopez, B. M.
Kang, H. S.
Kim, T. H.
Viterbo, V. S.
Kim, H. S.
Na, C. S.
Seo, K. S.
author_facet Lopez, B. M.
Kang, H. S.
Kim, T. H.
Viterbo, V. S.
Kim, H. S.
Na, C. S.
Seo, K. S.
author_sort Lopez, B. M.
collection PubMed
description The objective of this study was to evaluate the present conventional selection program of a swine nucleus farm and compare it with a new selection strategy employing genomic enhanced breeding value (GEBV) as the selection criteria. The ZPLAN+ software was employed to calculate and compare the genetic gain, total cost, return and profit of each selection strategy. The first strategy reflected the current conventional breeding program, which was a progeny test system (CS). The second strategy was a selection scheme based strictly on genomic information (GS1). The third scenario was the same as GS1, but the selection by GEBV was further supplemented by the performance test (GS2). The last scenario was a mixture of genomic information and progeny tests (GS3). The results showed that the accuracy of the selection index of young boars of GS1 was 26% higher than that of CS. On the other hand, both GS2 and GS3 gave 31% higher accuracy than CS for young boars. The annual monetary genetic gain of GS1, GS2 and GS3 was 10%, 12%, and 11% higher, respectively, than that of CS. As expected, the discounted costs of genomic selection strategies were higher than those of CS. The costs of GS1, GS2 and GS3 were 35%, 73%, and 89% higher than those of CS, respectively, assuming a genotyping cost of $120. As a result, the discounted profit per animal of GS1 and GS2 was 8% and 2% higher, respectively, than that of CS while GS3 was 6% lower. Comparison among genomic breeding scenarios revealed that GS1 was more profitable than GS2 and GS3. The genomic selection schemes, especially GS1 and GS2, were clearly superior to the conventional scheme in terms of monetary genetic gain and profit.
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spelling pubmed-48522242016-05-04 Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+ Lopez, B. M. Kang, H. S. Kim, T. H. Viterbo, V. S. Kim, H. S. Na, C. S. Seo, K. S. Asian-Australas J Anim Sci Article The objective of this study was to evaluate the present conventional selection program of a swine nucleus farm and compare it with a new selection strategy employing genomic enhanced breeding value (GEBV) as the selection criteria. The ZPLAN+ software was employed to calculate and compare the genetic gain, total cost, return and profit of each selection strategy. The first strategy reflected the current conventional breeding program, which was a progeny test system (CS). The second strategy was a selection scheme based strictly on genomic information (GS1). The third scenario was the same as GS1, but the selection by GEBV was further supplemented by the performance test (GS2). The last scenario was a mixture of genomic information and progeny tests (GS3). The results showed that the accuracy of the selection index of young boars of GS1 was 26% higher than that of CS. On the other hand, both GS2 and GS3 gave 31% higher accuracy than CS for young boars. The annual monetary genetic gain of GS1, GS2 and GS3 was 10%, 12%, and 11% higher, respectively, than that of CS. As expected, the discounted costs of genomic selection strategies were higher than those of CS. The costs of GS1, GS2 and GS3 were 35%, 73%, and 89% higher than those of CS, respectively, assuming a genotyping cost of $120. As a result, the discounted profit per animal of GS1 and GS2 was 8% and 2% higher, respectively, than that of CS while GS3 was 6% lower. Comparison among genomic breeding scenarios revealed that GS1 was more profitable than GS2 and GS3. The genomic selection schemes, especially GS1 and GS2, were clearly superior to the conventional scheme in terms of monetary genetic gain and profit. Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016-05 2016-01-18 /pmc/articles/PMC4852224/ /pubmed/26954222 http://dx.doi.org/10.5713/ajas.15.0842 Text en Copyright © 2016 by Asian-Australasian Journal of Animal Sciences This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Lopez, B. M.
Kang, H. S.
Kim, T. H.
Viterbo, V. S.
Kim, H. S.
Na, C. S.
Seo, K. S.
Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title_full Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title_fullStr Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title_full_unstemmed Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title_short Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+
title_sort optimization of swine breeding programs using genomic selection with zplan+
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852224/
https://www.ncbi.nlm.nih.gov/pubmed/26954222
http://dx.doi.org/10.5713/ajas.15.0842
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