Cargando…

The Effects of Glucagon-like Peptide-2 on the Tight Junction and Barrier Function in IPEC-J2 Cells through Phosphatidylinositol 3-kinase–Protein Kinase B–Mammalian Target of Rapamycin Signaling Pathway

Glucagon-like peptide-2 (GLP-2) is important for intestinal barrier function and regulation of tight junction (TJ) proteins, but the intracellular mechanisms of action remain undefined. The purpose of this research was to determine the protective effect of GLP-2 mediated TJ and transepithelial elect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Changsong, Jia, Gang, Deng, Qiuhong, Zhao, Hua, Chen, Xiaoling, Liu, Guangmang, Wang, Kangning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852237/ https://www.ncbi.nlm.nih.gov/pubmed/26954146 http://dx.doi.org/10.5713/ajas.15.0415

Ejemplares similares

Effect of Glucagon-like Peptide 2 on Tight Junction in Jejunal Epithelium of Weaned Pigs though MAPK Signaling Pathway
por: Yu, Changsong, et al.
Publicado: (2014)

β-Conglycinin Reduces the Tight Junction Occludin and ZO-1 Expression in IPEC-J2
por: Zhao, Yuan, et al.
Publicado: (2014)

Can phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibition ERase them all?
por: Meyer, Dominique S, et al.
Publicado: (2010)

Concerted action of berberine in the porcine intestinal epithelial model IPEC‐J2: Effects on tight junctions and apoptosis
por: Cornelius, Valeria, et al.
Publicado: (2022)

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting
por: De Cicco, Maristella, et al.
Publicado: (2015)

Osteopontin promotes gastric cancer progression via phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
por: Qin, Yue-Chao, et al.
Publicado: (2023)

Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin
por: Xie, Chengying, et al.
Publicado: (2017)

A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy
por: Goodman, Craig A., et al.
Publicado: (2010)

Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3′-kinase/protein kinase B/mammalian target of rapamycin pathway
por: Zhang, Meng-Hui, et al.
Publicado: (2022)

The Emerging Role of the Phosphatidylinositol 3-Kinase/ Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology
por: Martelli, Alberto M., et al.
Publicado: (2010)

Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors
por: Wanigasooriya, Kasun, et al.
Publicado: (2020)

Transmissible gastroenteritis virus and porcine epidemic diarrhoea virus infection induces dramatic changes in the tight junctions and microfilaments of polarized IPEC-J2 cells
por: Zhao, Shanshan, et al.
Publicado: (2014)

Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer
por: Elfiky, Aymen A, et al.
Publicado: (2011)

Lactobacillus reuteri I5007 modulates tight junction protein expression in IPEC-J2 cells with LPS stimulation and in newborn piglets under normal conditions
por: Yang, Fengjuan, et al.
Publicado: (2015)

Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway
por: Yan, Hui, et al.
Publicado: (2017)

Topoisomerase II alpha promotes gallbladder cancer proliferation and metastasis through activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
por: Lyu, Wen-Jie, et al.
Publicado: (2020)

Influence of Phosphatidylinositol-3-Kinase/Protein Kinase B-Mammalian Target of Rapamycin Signaling Pathway on the Neuropathic Pain Complicated by Nucleoside Reverse Transcriptase Inhibitors for the Treatment of HIV Infection
por: Cheng, Hao, et al.
Publicado: (2018)

Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of the Rapamycin Pathway-Related Protein Expression in Lung Squamous Cell Carcinoma and Its Correlation with Lymph Node Metastasis
por: Shi, Fang, et al.
Publicado: (2022)

Corrigendum: Topoisomerase II alpha promotes gallbladder cancer proliferation and metastasis through activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
Publicado: (2022)

Autophagy inhibition enhances colorectal cancer apoptosis induced by dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235
por: YANG, XIAOYU, et al.
Publicado: (2016)

Nontoxic-dose deoxynivalenol aggravates lipopolysaccharides-induced inflammation and tight junction disorder in IPEC-J2 cells through activation of NF-κB and LC3B
por: Ge, Lei, et al.
Publicado: (2020)

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment
por: Martelli, Alberto M., et al.
Publicado: (2012)

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity
por: Fokas, Emmanouil, et al.
Publicado: (2012)

Heterogeneity of Phosphatidylinositol-3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin Activation in Cancer: Is PI3K Isoform Specificity Important?
por: Cintas, Célia, et al.
Publicado: (2018)

Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks
por: Clayton, Emma L., et al.
Publicado: (2013)

Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2015)

Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments
por: Yan, Mengfei, et al.
Publicado: (2014)

VARIATIONS IN TIGHT AND GAP JUNCTIONS IN MAMMALIAN TISSUES
por: Friend, Daniel S., et al.
Publicado: (1972)

Modulation of Tight Junction Structure and Function by Kinases and Phosphatases Targeting Occludin
por: Dörfel, Max Johannes, et al.
Publicado: (2012)

Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes
por: Mathre, Swarna, et al.
Publicado: (2019)

Penetration of Fosfomycin into IPEC-J2 Cells in the Presence or Absence of Deoxynivalenol
por: Martínez, Guadalupe, et al.
Publicado: (2013)

Bacillus amyloliquefaciens Ameliorates H(2)O(2)-Induced Oxidative Damage by Regulating Transporters, Tight Junctions, and Apoptosis Gene Expression in Cell Line IPEC-1
por: Wu, Yanping, et al.
Publicado: (2019)

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica
por: Nakada-Tsukui, Kumiko, et al.
Publicado: (2019)

Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
por: Chen, Xinyu, et al.
Publicado: (2006)

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
Publicado: (1995)

The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior
por: Ramírez-Jarquín, Uri Nimrod, et al.
Publicado: (2020)

Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway
por: Chen, Lin, et al.
Publicado: (2019)

Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis
por: Zhao, Tingting, et al.
Publicado: (2019)

Effects of Different Methionine Sources on Methionine Metabolism in the IPEC-J2 Cells
por: Zuo, Fangrui, et al.
Publicado: (2019)

Effects of daidzein on antioxidant capacity in weaned pigs and IPEC-J2 cells
por: Li, Yanpin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7iveb0bl5qg1p0d8ebt6765jtc