BRAF Mutation Is Associated with Improved Local Control of Melanoma Brain Metastases Treated with Gamma Knife Radiosurgery

OBJECTIVES: Evidence has implicated a possible role of tumor mutation status on local control (LC) with radiotherapy. BRAF is a proto-oncogene that is mutated in approximately 50% of patients with melanoma. We sought to analyze the influence of BRAF status on LC of melanoma brain metastases (MBM) fo...

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Detalles Bibliográficos
Autores principales: Gallaher, Ian S., Watanabe, Yoichi, DeFor, Todd E., Dusenbery, Kathryn E., Lee, Chung K., Hunt, Matthew A., Lin, Hong-Yiou, Yuan, Jianling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852277/
https://www.ncbi.nlm.nih.gov/pubmed/27200295
http://dx.doi.org/10.3389/fonc.2016.00107

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