3-D structural interactions and quantitative structural toxicity studies of tyrosine derivatives intended for safe potent inflammation treatment

BACKGROUND: Drugs that inhibit cyclooxygenase-2 (COX-2) while sparing cyclooxygenase-1 (COX-1) represent a new attractive therapeutic development and offer new perspective for further use of COX-2 inhibitors. Intention of this work is to develop safer, selective COX-2 inhibitors that do not produce...

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Detalles Bibliográficos
Autores principales: Puratchikody, Ayarivan, Sriram, Dharmaraj, Umamaheswari, Appavoo, Irfan, Navabshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852405/
https://www.ncbi.nlm.nih.gov/pubmed/27141229
http://dx.doi.org/10.1186/s13065-016-0169-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852405/
https://www.ncbi.nlm.nih.gov/pubmed/27141229
http://dx.doi.org/10.1186/s13065-016-0169-9

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