Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells

BACKGROUND: Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Although oscillating glucose can induce a more deleterious effect than high glucos...

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Detalles Bibliográficos
Autores principales: La Sala, Lucia, Cattaneo, Monica, De Nigris, Valeria, Pujadas, Gemma, Testa, Roberto, Bonfigli, Anna R., Genovese, Stefano, Ceriello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852407/
https://www.ncbi.nlm.nih.gov/pubmed/27137793
http://dx.doi.org/10.1186/s12933-016-0390-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852407/
https://www.ncbi.nlm.nih.gov/pubmed/27137793
http://dx.doi.org/10.1186/s12933-016-0390-9

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