Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen(−/−))

BACKGROUND: Live attenuated Leishmania donovani parasites as LdCen(−/−) were shown to confer protective immunity against Leishmania infection in mice, hamsters, and dogs. Strong immunogenicity in dogs vaccinated with LdCen(−/−) has been previously reported, including increased antibody response favo...

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Detalles Bibliográficos
Autores principales: Viana, Kelvinson Fernandes, Fiuza, Jacqueline Araújo, Gannavaram, Sreenivas, Dey, Ranadhir, Selvapandiyan, Angamuthu, Bartholomeu, Daniella Castanheira, Silveira-Lemos, Denise da, Bueno, Lilian Lacerda, Dutra, Walderez Ornelas, Fujiwara, Ricardo Toshio, Nakhasi, Hira L., Giunchetti, Rodolfo Cordeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852444/
https://www.ncbi.nlm.nih.gov/pubmed/27136900
http://dx.doi.org/10.1186/s13071-016-1528-z

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