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Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates

BACKGROUND: Clinical assessment of depression is an important part of pre-surgical assessment among individuals with morbid obesity. However, there is no agreed-upon instrument to identify mood psychopathology in this population. We examined the reliability and criterion validity of the clinician-ad...

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Autores principales: Duarte-Guerra, Leorides Severo, Gorenstein, Clarice, Paiva-Medeiros, Paula Francinelle, Santo, Marco Aurélio, Lotufo Neto, Francisco, Wang, Yuan-Pang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852448/
https://www.ncbi.nlm.nih.gov/pubmed/27138750
http://dx.doi.org/10.1186/s12888-016-0823-8
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author Duarte-Guerra, Leorides Severo
Gorenstein, Clarice
Paiva-Medeiros, Paula Francinelle
Santo, Marco Aurélio
Lotufo Neto, Francisco
Wang, Yuan-Pang
author_facet Duarte-Guerra, Leorides Severo
Gorenstein, Clarice
Paiva-Medeiros, Paula Francinelle
Santo, Marco Aurélio
Lotufo Neto, Francisco
Wang, Yuan-Pang
author_sort Duarte-Guerra, Leorides Severo
collection PubMed
description BACKGROUND: Clinical assessment of depression is an important part of pre-surgical assessment among individuals with morbid obesity. However, there is no agreed-upon instrument to identify mood psychopathology in this population. We examined the reliability and criterion validity of the clinician-administered Montgomery-Åsberg Depression Rating Scale (MADRS) and the utility of a short version for bariatric surgery candidates. METHODS: The sample was 374 patients with obesity, consecutively recruited from the waiting list of a bariatric surgery clinic of University Hospital, Brazil: women 80 %, mean BMI 47 kg/m(2), mean age 43.0 years. The 10-item MADRS was analyzed against the SCID-I. Items that showed small relevance to sample’s characteristics and contribution to data variability were removed to develop the short 5-item version of scale. We calculated the sensitivity and specificity of cutoff points of both versions MADRS, and values were plotted as a receiver operating characteristic curve. RESULTS: For the 10-item MADRS, the Cronbach’s alpha coefficient was 0.93. When compared against SCID-I, the best cut-off threshold was 13/14, yielding sensitivity of 0.81 and specificity 0.85. Following items were removed: reduced appetite, reduced sleep, concentration difficulties, suicide thought and lassitude. The 5-item version showed an alpha coefficient of 0.94 and a best cut-off threshold of 10/11, yielding sensitivity of 0.81 and specificity 0.87. Similar overall ability to discriminate depression of almost 90 % was found for both 10-item and 5-item MADRS. CONCLUSION: The MADRS is a reliable and valid instrument to assess depressive symptoms among treatment-seeking bariatric patients. Systematic application of the abbreviated version of the MADRS can be recommended for enhancing the clinical detection of depression during perioperative period. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12888-016-0823-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-48524482016-05-03 Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates Duarte-Guerra, Leorides Severo Gorenstein, Clarice Paiva-Medeiros, Paula Francinelle Santo, Marco Aurélio Lotufo Neto, Francisco Wang, Yuan-Pang BMC Psychiatry Research Article BACKGROUND: Clinical assessment of depression is an important part of pre-surgical assessment among individuals with morbid obesity. However, there is no agreed-upon instrument to identify mood psychopathology in this population. We examined the reliability and criterion validity of the clinician-administered Montgomery-Åsberg Depression Rating Scale (MADRS) and the utility of a short version for bariatric surgery candidates. METHODS: The sample was 374 patients with obesity, consecutively recruited from the waiting list of a bariatric surgery clinic of University Hospital, Brazil: women 80 %, mean BMI 47 kg/m(2), mean age 43.0 years. The 10-item MADRS was analyzed against the SCID-I. Items that showed small relevance to sample’s characteristics and contribution to data variability were removed to develop the short 5-item version of scale. We calculated the sensitivity and specificity of cutoff points of both versions MADRS, and values were plotted as a receiver operating characteristic curve. RESULTS: For the 10-item MADRS, the Cronbach’s alpha coefficient was 0.93. When compared against SCID-I, the best cut-off threshold was 13/14, yielding sensitivity of 0.81 and specificity 0.85. Following items were removed: reduced appetite, reduced sleep, concentration difficulties, suicide thought and lassitude. The 5-item version showed an alpha coefficient of 0.94 and a best cut-off threshold of 10/11, yielding sensitivity of 0.81 and specificity 0.87. Similar overall ability to discriminate depression of almost 90 % was found for both 10-item and 5-item MADRS. CONCLUSION: The MADRS is a reliable and valid instrument to assess depressive symptoms among treatment-seeking bariatric patients. Systematic application of the abbreviated version of the MADRS can be recommended for enhancing the clinical detection of depression during perioperative period. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12888-016-0823-8) contains supplementary material, which is available to authorized users. BioMed Central 2016-04-30 /pmc/articles/PMC4852448/ /pubmed/27138750 http://dx.doi.org/10.1186/s12888-016-0823-8 Text en © Duarte-Guerra et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Duarte-Guerra, Leorides Severo
Gorenstein, Clarice
Paiva-Medeiros, Paula Francinelle
Santo, Marco Aurélio
Lotufo Neto, Francisco
Wang, Yuan-Pang
Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title_full Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title_fullStr Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title_full_unstemmed Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title_short Clinical utility of the Montgomery-Åsberg Depression Rating Scale for the detection of depression among bariatric surgery candidates
title_sort clinical utility of the montgomery-åsberg depression rating scale for the detection of depression among bariatric surgery candidates
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852448/
https://www.ncbi.nlm.nih.gov/pubmed/27138750
http://dx.doi.org/10.1186/s12888-016-0823-8
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