DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors

The DNA damage response (DDR) plays a central role in preserving genome integrity. Recently, we reported that the endoribonucleases DICER and DROSHA contribute to DDR activation by generating small non-coding RNAs, termed DNA damage response RNA (DDRNA), carrying the sequence of the damaged locus. I...

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Detalles Bibliográficos
Autores principales: Francia, Sofia, Cabrini, Matteo, Matti, Valentina, Oldani, Amanda, d'Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852722/
https://www.ncbi.nlm.nih.gov/pubmed/26906421
http://dx.doi.org/10.1242/jcs.182188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852722/
https://www.ncbi.nlm.nih.gov/pubmed/26906421
http://dx.doi.org/10.1242/jcs.182188

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