Cargando…
DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors
The DNA damage response (DDR) plays a central role in preserving genome integrity. Recently, we reported that the endoribonucleases DICER and DROSHA contribute to DDR activation by generating small non-coding RNAs, termed DNA damage response RNA (DDRNA), carrying the sequence of the damaged locus. I...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852722/ https://www.ncbi.nlm.nih.gov/pubmed/26906421 http://dx.doi.org/10.1242/jcs.182188 |