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Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress
Replications forks are routinely hindered by different endogenous stresses. Because homologous recombination plays a pivotal role in the reactivation of arrested replication forks, defects in homologous recombination reveal the initial endogenous stress(es). Homologous recombination-defective cells...
Autores principales: | Wilhelm, Therese, Ragu, Sandrine, Magdalou, Indiana, Machon, Christelle, Dardillac, Elodie, Técher, Hervé, Guitton, Jérôme, Debatisse, Michelle, Lopez, Bernard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852921/ https://www.ncbi.nlm.nih.gov/pubmed/27135742 http://dx.doi.org/10.1371/journal.pgen.1006007 |
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