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Overrepresentation of IL-10-Expressing B Cells Suppresses Cytotoxic CD4(+) T Cell Activity in HBV-Induced Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a common cancer with poor prognosis and low five-year survival rate. A strong and effective CD4(+) T cell-mediated cytotoxicity was associated with better survival and low recurrence rate in HCC, but the regulatory mechanism that controls CD4(+) T cell cytotoxicity...

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Detalles Bibliográficos
Autores principales: Xue, Hongwei, Lin, Fuhuang, Tan, Hongwu, Zhu, Zun-Qiang, Zhang, Zhang-Yun, Zhao, Ludong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852942/
https://www.ncbi.nlm.nih.gov/pubmed/27136203
http://dx.doi.org/10.1371/journal.pone.0154815