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The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed
BACKGROUND: The purpose of the study was to analyse the dosimetric differences when using 10 MV instead of 6 MV for VMAT treatment plans for post-prostatectomy irradiation of the prostate bed. METHODS AND MATERIALS: Ten post-prostatectomy prostate bed irradiation cases previously treated using 6 MV...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852958/ https://www.ncbi.nlm.nih.gov/pubmed/27247557 http://dx.doi.org/10.1515/raon-2016-0012 |
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author | Kleiner, Henry Podgorsak, Matthew B. |
author_facet | Kleiner, Henry Podgorsak, Matthew B. |
author_sort | Kleiner, Henry |
collection | PubMed |
description | BACKGROUND: The purpose of the study was to analyse the dosimetric differences when using 10 MV instead of 6 MV for VMAT treatment plans for post-prostatectomy irradiation of the prostate bed. METHODS AND MATERIALS: Ten post-prostatectomy prostate bed irradiation cases previously treated using 6 MV with volumetric modulated arc therapy (VMAT) were re-planned using 10 MV with VMAT. Prescription dose was 66.6 Gy with 1.8 Gy per fraction for 37 daily fractions. The same structure set, number of arcs, field sizes, and minimum dose to the Planning Target Volume (PTV) were used for both 6 MV and 10 MV plans. Results were collected for dose to Organs at Risk (OAR) constraints, dose to the target structures, number of monitor units for each arc, Body V(5), Conformity Index, and Integral Dose. The mean values were used to compare the 6 MV and 10 MV results. To determine the statistical significance of the results, a paired Student t test and power analysis was performed. RESULTS: Statistically significant lower mean values were observed for the OAR dose constraints for the rectum, bladder-Clinical Target Volume (bladder-CTV), left femoral head, and right femoral head. Also, statistically significant lower mean values were observed for the Body V(5), Conformity Index, and Integral Dose. CONCLUSIONS: Several dosimetric benefits were observed when using 10 MV instead of 6 MV for VMAT based treatment plans. Benefits include sparing more dose from the OAR while still maintaining the same dose coverage to the PTV. Other benefits include lower Body V (5,)Conformity Index, and Integral Dose. |
format | Online Article Text |
id | pubmed-4852958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | De Gruyter |
record_format | MEDLINE/PubMed |
spelling | pubmed-48529582016-06-01 The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed Kleiner, Henry Podgorsak, Matthew B. Radiol Oncol Research Article BACKGROUND: The purpose of the study was to analyse the dosimetric differences when using 10 MV instead of 6 MV for VMAT treatment plans for post-prostatectomy irradiation of the prostate bed. METHODS AND MATERIALS: Ten post-prostatectomy prostate bed irradiation cases previously treated using 6 MV with volumetric modulated arc therapy (VMAT) were re-planned using 10 MV with VMAT. Prescription dose was 66.6 Gy with 1.8 Gy per fraction for 37 daily fractions. The same structure set, number of arcs, field sizes, and minimum dose to the Planning Target Volume (PTV) were used for both 6 MV and 10 MV plans. Results were collected for dose to Organs at Risk (OAR) constraints, dose to the target structures, number of monitor units for each arc, Body V(5), Conformity Index, and Integral Dose. The mean values were used to compare the 6 MV and 10 MV results. To determine the statistical significance of the results, a paired Student t test and power analysis was performed. RESULTS: Statistically significant lower mean values were observed for the OAR dose constraints for the rectum, bladder-Clinical Target Volume (bladder-CTV), left femoral head, and right femoral head. Also, statistically significant lower mean values were observed for the Body V(5), Conformity Index, and Integral Dose. CONCLUSIONS: Several dosimetric benefits were observed when using 10 MV instead of 6 MV for VMAT based treatment plans. Benefits include sparing more dose from the OAR while still maintaining the same dose coverage to the PTV. Other benefits include lower Body V (5,)Conformity Index, and Integral Dose. De Gruyter 2016-02-22 /pmc/articles/PMC4852958/ /pubmed/27247557 http://dx.doi.org/10.1515/raon-2016-0012 Text en © 2016 Radiol Oncol |
spellingShingle | Research Article Kleiner, Henry Podgorsak, Matthew B. The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title | The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title_full | The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title_fullStr | The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title_full_unstemmed | The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title_short | The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
title_sort | dosimetric significance of using 10 mv photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852958/ https://www.ncbi.nlm.nih.gov/pubmed/27247557 http://dx.doi.org/10.1515/raon-2016-0012 |
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