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Malignant gliomas: old and new systemic treatment approaches
BACKGROUND: Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and ra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852970/ https://www.ncbi.nlm.nih.gov/pubmed/27247544 http://dx.doi.org/10.1515/raon-2015-0003 |
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author | Mesti, Tanja Ocvirk, Janja |
author_facet | Mesti, Tanja Ocvirk, Janja |
author_sort | Mesti, Tanja |
collection | PubMed |
description | BACKGROUND: Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and radiotherapy. Chemotherapy used as an adjuvant treatment or at recurrence had a marginal role. CONCLUSIONS: Nowadays, the treatment of malignant gliomas requires a multidisciplinary approach. The treatment includes surgery, radiotherapy and chemotherapy. The chosen approach is more complex and individually adjusted. By that, the effect on the survival and quality of life is notable higher. |
format | Online Article Text |
id | pubmed-4852970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | De Gruyter |
record_format | MEDLINE/PubMed |
spelling | pubmed-48529702016-06-01 Malignant gliomas: old and new systemic treatment approaches Mesti, Tanja Ocvirk, Janja Radiol Oncol Review BACKGROUND: Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and radiotherapy. Chemotherapy used as an adjuvant treatment or at recurrence had a marginal role. CONCLUSIONS: Nowadays, the treatment of malignant gliomas requires a multidisciplinary approach. The treatment includes surgery, radiotherapy and chemotherapy. The chosen approach is more complex and individually adjusted. By that, the effect on the survival and quality of life is notable higher. De Gruyter 2016-04-23 /pmc/articles/PMC4852970/ /pubmed/27247544 http://dx.doi.org/10.1515/raon-2015-0003 Text en © 2016 Radiol Oncol |
spellingShingle | Review Mesti, Tanja Ocvirk, Janja Malignant gliomas: old and new systemic treatment approaches |
title | Malignant gliomas: old and new systemic treatment approaches |
title_full | Malignant gliomas: old and new systemic treatment approaches |
title_fullStr | Malignant gliomas: old and new systemic treatment approaches |
title_full_unstemmed | Malignant gliomas: old and new systemic treatment approaches |
title_short | Malignant gliomas: old and new systemic treatment approaches |
title_sort | malignant gliomas: old and new systemic treatment approaches |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852970/ https://www.ncbi.nlm.nih.gov/pubmed/27247544 http://dx.doi.org/10.1515/raon-2015-0003 |
work_keys_str_mv | AT mestitanja malignantgliomasoldandnewsystemictreatmentapproaches AT ocvirkjanja malignantgliomasoldandnewsystemictreatmentapproaches |