Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation

Since elevated expression of matrix metalloproteinase (MMP)-2 and MMP-9 is commonly observed in several malignant tumors, MMPs have been widely reported as key factors in the design of drug delivery systems. Several strategies have been proposed to develop MMPs-responsive nanoparticles to deliver ch...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Wang, Xiaofei, Zhong, Weitong, Ren, Xiaoqing, Sha, Xianyi, Fang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853011/
https://www.ncbi.nlm.nih.gov/pubmed/27217744
http://dx.doi.org/10.2147/IJN.S101030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853011/
https://www.ncbi.nlm.nih.gov/pubmed/27217744
http://dx.doi.org/10.2147/IJN.S101030

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