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Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation

Since elevated expression of matrix metalloproteinase (MMP)-2 and MMP-9 is commonly observed in several malignant tumors, MMPs have been widely reported as key factors in the design of drug delivery systems. Several strategies have been proposed to develop MMPs-responsive nanoparticles to deliver ch...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoyan, Wang, Xiaofei, Zhong, Weitong, Ren, Xiaoqing, Sha, Xianyi, Fang, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853011/ https://www.ncbi.nlm.nih.gov/pubmed/27217744 http://dx.doi.org/10.2147/IJN.S101030

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