A single flexible RNAPII-CTD integrates many different transcriptional programs

The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidenc...

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Detalles Bibliográficos
Autores principales: Aristizabal, Maria J., Kobor, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853039/
https://www.ncbi.nlm.nih.gov/pubmed/26985717
http://dx.doi.org/10.1080/21541264.2016.1163451
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author Aristizabal, Maria J.
Kobor, Michael S.
author_facet Aristizabal, Maria J.
Kobor, Michael S.
author_sort Aristizabal, Maria J.
collection PubMed
description The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidence of species- and loci-specific functions for the RNAPII-CTD.
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spelling pubmed-48530392016-05-10 A single flexible RNAPII-CTD integrates many different transcriptional programs Aristizabal, Maria J. Kobor, Michael S. Transcription Point-of-View The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidence of species- and loci-specific functions for the RNAPII-CTD. Taylor & Francis 2016-03-17 /pmc/articles/PMC4853039/ /pubmed/26985717 http://dx.doi.org/10.1080/21541264.2016.1163451 Text en © 2016 The Author(s). Published with license by Taylor & Francis. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Point-of-View
Aristizabal, Maria J.
Kobor, Michael S.
A single flexible RNAPII-CTD integrates many different transcriptional programs
title A single flexible RNAPII-CTD integrates many different transcriptional programs
title_full A single flexible RNAPII-CTD integrates many different transcriptional programs
title_fullStr A single flexible RNAPII-CTD integrates many different transcriptional programs
title_full_unstemmed A single flexible RNAPII-CTD integrates many different transcriptional programs
title_short A single flexible RNAPII-CTD integrates many different transcriptional programs
title_sort single flexible rnapii-ctd integrates many different transcriptional programs
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853039/
https://www.ncbi.nlm.nih.gov/pubmed/26985717
http://dx.doi.org/10.1080/21541264.2016.1163451
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