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Regulation of T Cell Differentiation and Function by EZH2

The enhancer of zeste homolog 2 (EZH2), one of the polycomb-group proteins, is the catalytic subunit of Polycomb-repressive complex 2 (PRC2) and induces the trimethylation of the histone H3 lysine 27 (H3K27me3) promoting epigenetic gene silencing. EZH2 contains a SET domain promoting the methyltrans...

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Detalles Bibliográficos
Autores principales:	Karantanos, Theodoros, Christofides, Anthos, Bardhan, Kankana, Li, Lequn, Boussiotis, Vassiliki A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853381/ https://www.ncbi.nlm.nih.gov/pubmed/27199994 http://dx.doi.org/10.3389/fimmu.2016.00172

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