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House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens, Mainly via a TNF-α-Dependent Pathway

PURPOSE: Chitin is a potent adjuvant in the development of immune response to inhaled allergens in the airways. According to other studies, chitin is known as multi-faced adjuvants which can induce Th2 responses. Recently, we found that TNF-α is a key mediator in the development of Th2 cell response...

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Detalles Bibliográficos
Autores principales: Choi, Jun-Pyo, Lee, Sang-Min, Choi, Hyun-Il, Kim, Min-Hye, Jeon, Seong Gyu, Jang, Myoung Ho, Jee, Young-Koo, Yang, Sanghwa, Cho, Young-Joo, Kim, Yoon-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853514/
https://www.ncbi.nlm.nih.gov/pubmed/27126730
http://dx.doi.org/10.4168/aair.2016.8.4.362