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The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation

Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the...

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Autores principales: Julliard, Walker A, Meyer, Keith C, De Oliveira, Nilto C, Osaki, Satoru, Cornwell, Richard C, Sonetti, David A, Maloney, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853536/
https://www.ncbi.nlm.nih.gov/pubmed/26621135
http://dx.doi.org/10.1136/thoraxjnl-2015-207354
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author Julliard, Walker A
Meyer, Keith C
De Oliveira, Nilto C
Osaki, Satoru
Cornwell, Richard C
Sonetti, David A
Maloney, James D
author_facet Julliard, Walker A
Meyer, Keith C
De Oliveira, Nilto C
Osaki, Satoru
Cornwell, Richard C
Sonetti, David A
Maloney, James D
author_sort Julliard, Walker A
collection PubMed
description Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the outcomes of 279 consecutive SLT recipients transplanted at our centre, and the patients were split into four groups based on their mean pulmonary artery pressure values. Outcomes, including long-term survival and primary graft dysfunction, did not differ significantly for patients with versus without PH, even when PH was severe. We suggest that SLT can be performed safely in patients with ALD-associated PH.
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spelling pubmed-48535362016-05-06 The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation Julliard, Walker A Meyer, Keith C De Oliveira, Nilto C Osaki, Satoru Cornwell, Richard C Sonetti, David A Maloney, James D Thorax Chest Clinic Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the outcomes of 279 consecutive SLT recipients transplanted at our centre, and the patients were split into four groups based on their mean pulmonary artery pressure values. Outcomes, including long-term survival and primary graft dysfunction, did not differ significantly for patients with versus without PH, even when PH was severe. We suggest that SLT can be performed safely in patients with ALD-associated PH. BMJ Publishing Group 2016-05 2015-12-01 /pmc/articles/PMC4853536/ /pubmed/26621135 http://dx.doi.org/10.1136/thoraxjnl-2015-207354 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Chest Clinic
Julliard, Walker A
Meyer, Keith C
De Oliveira, Nilto C
Osaki, Satoru
Cornwell, Richard C
Sonetti, David A
Maloney, James D
The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title_full The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title_fullStr The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title_full_unstemmed The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title_short The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
title_sort presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
topic Chest Clinic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853536/
https://www.ncbi.nlm.nih.gov/pubmed/26621135
http://dx.doi.org/10.1136/thoraxjnl-2015-207354
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