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The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation
Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853536/ https://www.ncbi.nlm.nih.gov/pubmed/26621135 http://dx.doi.org/10.1136/thoraxjnl-2015-207354 |
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author | Julliard, Walker A Meyer, Keith C De Oliveira, Nilto C Osaki, Satoru Cornwell, Richard C Sonetti, David A Maloney, James D |
author_facet | Julliard, Walker A Meyer, Keith C De Oliveira, Nilto C Osaki, Satoru Cornwell, Richard C Sonetti, David A Maloney, James D |
author_sort | Julliard, Walker A |
collection | PubMed |
description | Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the outcomes of 279 consecutive SLT recipients transplanted at our centre, and the patients were split into four groups based on their mean pulmonary artery pressure values. Outcomes, including long-term survival and primary graft dysfunction, did not differ significantly for patients with versus without PH, even when PH was severe. We suggest that SLT can be performed safely in patients with ALD-associated PH. |
format | Online Article Text |
id | pubmed-4853536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48535362016-05-06 The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation Julliard, Walker A Meyer, Keith C De Oliveira, Nilto C Osaki, Satoru Cornwell, Richard C Sonetti, David A Maloney, James D Thorax Chest Clinic Advanced lung disease (ALD) that requires lung transplantation (LTX) is frequently associated with pulmonary hypertension (PH). Whether the presence of PH significantly affects the outcomes following single-lung transplantation (SLT) remains controversial. Therefore, we retrospectively examined the outcomes of 279 consecutive SLT recipients transplanted at our centre, and the patients were split into four groups based on their mean pulmonary artery pressure values. Outcomes, including long-term survival and primary graft dysfunction, did not differ significantly for patients with versus without PH, even when PH was severe. We suggest that SLT can be performed safely in patients with ALD-associated PH. BMJ Publishing Group 2016-05 2015-12-01 /pmc/articles/PMC4853536/ /pubmed/26621135 http://dx.doi.org/10.1136/thoraxjnl-2015-207354 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Chest Clinic Julliard, Walker A Meyer, Keith C De Oliveira, Nilto C Osaki, Satoru Cornwell, Richard C Sonetti, David A Maloney, James D The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title | The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title_full | The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title_fullStr | The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title_full_unstemmed | The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title_short | The presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
title_sort | presence or severity of pulmonary hypertension does not affect outcomes for single-lung transplantation |
topic | Chest Clinic |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853536/ https://www.ncbi.nlm.nih.gov/pubmed/26621135 http://dx.doi.org/10.1136/thoraxjnl-2015-207354 |
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