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Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome

BACKGROUND: Beyond genetics, epigenetics alterations and especially those related to DNA methylation, play key roles in the pathogenesis of autoimmune diseases such as primary Sjögren's syndrome (pSS) and systemic lupus erythematosus. This study aimed to assess the role of methylation deregulat...

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Detalles Bibliográficos
Autores principales: Miceli-Richard, Corinne, Wang-Renault, Shu-Fang, Boudaoud, Saida, Busato, Florence, Lallemand, Céline, Bethune, Kevin, Belkhir, Rakiba, Nocturne, Gaétane, Mariette, Xavier, Tost, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853580/
https://www.ncbi.nlm.nih.gov/pubmed/26183421
http://dx.doi.org/10.1136/annrheumdis-2014-206998