Cargando…

Synovial fluid hyaluronan mediates MSC attachment to cartilage, a potential novel mechanism contributing to cartilage repair in osteoarthritis using knee joint distraction

OBJECTIVES: Knee joint distraction (KJD) is a novel, but poorly understood, treatment for osteoarthritis (OA) associated with remarkable ‘spontaneous’ cartilage repair in which resident synovial fluid (SF) multipotential mesenchymal stromal cells (MSCs) may play a role. We hypothesised that SF hyalu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baboolal, Thomas G, Mastbergen, Simon C, Jones, Elena, Calder, Stuart J, Lafeber, Floris P J G, McGonagle, Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853581/ https://www.ncbi.nlm.nih.gov/pubmed/25948596 http://dx.doi.org/10.1136/annrheumdis-2014-206847

Ejemplares similares

Gene Expression Signatures of Synovial Fluid Multipotent Stromal Cells in Advanced Knee Osteoarthritis and Following Knee Joint Distraction
por: Sanjurjo-Rodriguez, Clara, et al.
Publicado: (2020)

Knee joint distraction results in MRI cartilage thickness increase up to 10 years after treatment
por: Jansen, Mylène P, et al.
Publicado: (2021)

The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period
por: Teunissen, M., et al.
Publicado: (2022)

Device-Based Enrichment of Knee Joint Synovial Cells to Drive MSC Chondrogenesis Without Prior Culture Expansion In Vitro: A Step Closer to 1-Stage Orthopaedic Procedures
por: Altaie, Ala, et al.
Publicado: (2021)

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis
por: Nalesso, Giovanna, et al.
Publicado: (2017)

Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage
por: Soul, Jamie, et al.
Publicado: (2018)

Changes in Cartilage Thickness and Denuded Bone Area after Knee Joint Distraction and High Tibial Osteotomy—Post-Hoc Analyses of Two Randomized Controlled Trials
por: Jansen, Mylène P., et al.
Publicado: (2021)

Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy
por: Besselink, Nick J., et al.
Publicado: (2018)

The molecular profile of synovial fluid changes upon joint distraction and is associated with clinical response in knee osteoarthritis
por: Watt, F.E., et al.
Publicado: (2020)

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage
por: Vasheghani, Faezeh, et al.
Publicado: (2015)

Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration
por: Temple-Wong, Michele M., et al.
Publicado: (2016)

Role of vascular channels as a novel mechanism for subchondral bone damage at cruciate ligament entheses in osteoarthritis and inflammatory arthritis
por: Binks, D A, et al.
Publicado: (2015)

Benefits of Ilizarov automated bone distraction for nerves and articular cartilage in experimental leg lengthening
por: Shchudlo, Nathalia, et al.
Publicado: (2017)

Significant synovial pathology in a meniscectomy model of osteoarthritis: modification by intra-articular hyaluronan therapy
por: Smith, M. M., et al.
Publicado: (2008)

A homeostatic function of CXCR2 signalling in articular cartilage
por: Sherwood, Joanna, et al.
Publicado: (2015)

Knee joint distraction in regular care for treatment of knee osteoarthritis: A comparison with clinical trial data
por: Jansen, Mylène P., et al.
Publicado: (2020)

Identification of Novel Targets of Knee Osteoarthritis Shared by Cartilage and Synovial Tissue
por: Li, Chenshuang, et al.
Publicado: (2020)

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction
por: Rhee, Jinseol, et al.
Publicado: (2017)

Fib3-3 as a Biomarker for Osteoarthritis in a Rat Model with Metabolic Dysregulation
por: de Visser, Huub M., et al.
Publicado: (2018)

Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study
por: Mastbergen, Simon C, et al.
Publicado: (2006)

Enhanced Extracellular Matrix Breakdown Characterizes the Early Distraction Phase of Canine Knee Joint Distraction
por: Teunissen, Michelle, et al.
Publicado: (2021)

Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage
por: Hui, Wang, et al.
Publicado: (2016)

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology
por: Huesa, Carmen, et al.
Publicado: (2016)

Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study
por: Intema, Femke, et al.
Publicado: (2011)

Mobilisation of Joint-resident Mesenchymal Stromal Cells for Articular Cartilage Regeneration
por: Khan, Alam Khalil, et al.
Publicado: (2017)

Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis
por: Xu, Lingxiao, et al.
Publicado: (2016)

Toward New Assessment of Knee Cartilage Degeneration
por: Aubonnet, Romain, et al.
Publicado: (2022)

Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis
por: Skiöldebrand, E., et al.
Publicado: (2017)

A Novel Arthroscopic Technique for Intraoperative Mobilization of Synovial Mesenchymal Stem Cells
por: Baboolal, Thomas G., et al.
Publicado: (2018)

MSC-EV therapy for bone/cartilage diseases
por: Kodama, Joe, et al.
Publicado: (2022)

Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
por: Eldridge, Suzanne, et al.
Publicado: (2016)

Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model
por: LaBranche, Timothy P, et al.
Publicado: (2017)

The synovial surface of the articular cartilage
por: Basso, Petra, et al.
Publicado: (2020)

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis
por: Coutinho de Almeida, Rodrigo, et al.
Publicado: (2022)

Chondromodulin is necessary for cartilage callus distraction in mice
por: Yukata, Kiminori, et al.
Publicado: (2023)

Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes
por: Yatabe, T, et al.
Publicado: (2009)

Anomalous Behavior of Hyaluronan Crosslinking Due to the Presence of Excess Phospholipids in the Articular Cartilage System of Osteoarthritis
por: Bełdowski, Piotr, et al.
Publicado: (2017)

Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism
por: Li, Jun, et al.
Publicado: (2012)

Priming Adipose-Derived Mesenchymal Stem Cells with Hyaluronan Alters Growth Kinetics and Increases Attachment to Articular Cartilage
por: Succar, Peter, et al.
Publicado: (2016)

Quantitative Cartilage Imaging in Knee Osteoarthritis
por: Eckstein, Felix, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_u3lkm2sgl56ho5c80qsh60b5gb