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Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography

This work proposes a dedicated statistical algorithm to perform a direct reconstruction of material-decomposed images from data acquired with photon-counting detectors (PCDs) in computed tomography. It is based on local approximations (surrogates) of the negative logarithmic Poisson probability func...

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Detalles Bibliográficos
Autores principales: Weidinger, Thomas, Buzug, Thorsten M., Flohr, Thomas, Kappler, Steffen, Stierstorfer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853599/
https://www.ncbi.nlm.nih.gov/pubmed/27195003
http://dx.doi.org/10.1155/2016/5871604
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author Weidinger, Thomas
Buzug, Thorsten M.
Flohr, Thomas
Kappler, Steffen
Stierstorfer, Karl
author_facet Weidinger, Thomas
Buzug, Thorsten M.
Flohr, Thomas
Kappler, Steffen
Stierstorfer, Karl
author_sort Weidinger, Thomas
collection PubMed
description This work proposes a dedicated statistical algorithm to perform a direct reconstruction of material-decomposed images from data acquired with photon-counting detectors (PCDs) in computed tomography. It is based on local approximations (surrogates) of the negative logarithmic Poisson probability function. Exploiting the convexity of this function allows for parallel updates of all image pixels. Parallel updates can compensate for the rather slow convergence that is intrinsic to statistical algorithms. We investigate the accuracy of the algorithm for ideal photon-counting detectors. Complementarily, we apply the algorithm to simulation data of a realistic PCD with its spectral resolution limited by K-escape, charge sharing, and pulse-pileup. For data from both an ideal and realistic PCD, the proposed algorithm is able to correct beam-hardening artifacts and quantitatively determine the material fractions of the chosen basis materials. Via regularization we were able to achieve a reduction of image noise for the realistic PCD that is up to 90% lower compared to material images form a linear, image-based material decomposition using FBP images. Additionally, we find a dependence of the algorithms convergence speed on the threshold selection within the PCD.
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spelling pubmed-48535992016-05-18 Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography Weidinger, Thomas Buzug, Thorsten M. Flohr, Thomas Kappler, Steffen Stierstorfer, Karl Int J Biomed Imaging Research Article This work proposes a dedicated statistical algorithm to perform a direct reconstruction of material-decomposed images from data acquired with photon-counting detectors (PCDs) in computed tomography. It is based on local approximations (surrogates) of the negative logarithmic Poisson probability function. Exploiting the convexity of this function allows for parallel updates of all image pixels. Parallel updates can compensate for the rather slow convergence that is intrinsic to statistical algorithms. We investigate the accuracy of the algorithm for ideal photon-counting detectors. Complementarily, we apply the algorithm to simulation data of a realistic PCD with its spectral resolution limited by K-escape, charge sharing, and pulse-pileup. For data from both an ideal and realistic PCD, the proposed algorithm is able to correct beam-hardening artifacts and quantitatively determine the material fractions of the chosen basis materials. Via regularization we were able to achieve a reduction of image noise for the realistic PCD that is up to 90% lower compared to material images form a linear, image-based material decomposition using FBP images. Additionally, we find a dependence of the algorithms convergence speed on the threshold selection within the PCD. Hindawi Publishing Corporation 2016 2016-03-17 /pmc/articles/PMC4853599/ /pubmed/27195003 http://dx.doi.org/10.1155/2016/5871604 Text en Copyright © 2016 Thomas Weidinger et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Weidinger, Thomas
Buzug, Thorsten M.
Flohr, Thomas
Kappler, Steffen
Stierstorfer, Karl
Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title_full Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title_fullStr Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title_full_unstemmed Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title_short Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography
title_sort polychromatic iterative statistical material image reconstruction for photon-counting computed tomography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853599/
https://www.ncbi.nlm.nih.gov/pubmed/27195003
http://dx.doi.org/10.1155/2016/5871604
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