Cargando…

Relaxin Receptor RXFP1 and RXFP2 Expression in Ligament, Tendon, and Shoulder Joint Capsule of Rats

Numerous musculoskeletal disorders are caused by thickened ligament, tendon stiffness, or fibrosis of joint capsule. Relaxin, a peptide hormone, can exert collagenolytic effect on ligamentous and fibrotic tissues. We hypothesized that local injection of relaxin could be used to treat entrapment neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jae Hyung, Lee, Sang Kwang, Lee, Seong Kyu, Kim, Joo Heon, Fredericson, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853680/ https://www.ncbi.nlm.nih.gov/pubmed/27247510 http://dx.doi.org/10.3346/jkms.2016.31.6.983

Ejemplares similares

Sex-Steroid Regulation of Relaxin Receptor Isoforms (RXFP1 & RXFP2) Expression in the Patellar Tendon and Lateral Collateral Ligament of Female WKY Rats
por: Dehghan, Firouzeh, et al.
Publicado: (2014)

Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat
por: Filonzi, Marcelo, et al.
Publicado: (2007)

Changes in Knee Laxity and Relaxin Receptor Isoforms Expression (RXFP1/RXFP2) in the Knee throughout Estrous Cycle Phases in Rodents
por: Dehghan, Firouzeh, et al.
Publicado: (2016)

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3
por: Bathgate, Ross A. D., et al.
Publicado: (2013)

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1
por: Kocan, Martina, et al.
Publicado: (2017)

The Relaxin-3 Receptor, RXFP3, Is a Modulator of Aging-Related Disease
por: Leysen, Hanne, et al.
Publicado: (2022)

Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4)
por: Chen, Yan, et al.
Publicado: (2023)

In a Class of Their Own – RXFP1 and RXFP2 are Unique Members of the LGR Family
por: Petrie, Emma J., et al.
Publicado: (2015)

Relaxin’ the brain: a case for targeting the nucleus incertus network and relaxin‐3/RXFP3 system in neuropsychiatric disorders
por: Kumar, Jigna Rajesh, et al.
Publicado: (2016)

Relaxin-3/RXFP3 networks: an emerging target for the treatment of depression and other neuropsychiatric diseases?
por: Smith, Craig M., et al.
Publicado: (2014)

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1
por: Sethi, Ashish, et al.
Publicado: (2016)

Relaxin-3 Receptor (RXFP3) Signalling Mediates Stress-Related Alcohol Preference in Mice
por: Walker, Andrew W., et al.
Publicado: (2015)

Relaxin-3/RXFP3 Signaling and Neuroendocrine Function – A Perspective on Extrinsic Hypothalamic Control
por: Ganella, Despina E., et al.
Publicado: (2013)

In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis
por: McBride, Andrew, et al.
Publicado: (2017)

The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
por: Chen, Ting‐Yun, et al.
Publicado: (2020)

Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory
por: Gil-Miravet, Isis, et al.
Publicado: (2021)

Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: A candidate gene approach
por: Wong, Win Lee Edwin, et al.
Publicado: (2023)

GABAergic Neurons in the Rat Medial Septal Complex Express Relaxin-3 Receptor (RXFP3) mRNA
por: Albert-Gascó, Hector, et al.
Publicado: (2018)

Relaxin 2/RXFP1 Signaling Induces Cell Invasion via the β-Catenin Pathway in Endometrial Cancer
por: Fue, Misaki, et al.
Publicado: (2018)

Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis
por: Hoare, Bradley L., et al.
Publicado: (2018)

Synthetic short-chain peptide analogues of H1 relaxin lack affinity for the RXFP1 receptor and relaxin-like bioactivity. Clues to a better understanding of relaxin agonist design
por: D'Ercole, Annunziata, et al.
Publicado: (2022)

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1
por: Hossain, Mohammed Akhter, et al.
Publicado: (2016)

Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice
por: Lewis, Jo E., et al.
Publicado: (2022)

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules
por: Bruell, Shoni, et al.
Publicado: (2013)

Differential Level of RXFP3 Expression in Dopaminergic Neurons Within the Arcuate Nucleus, Dorsomedial Hypothalamus and Ventral Tegmental Area of RXFP3-Cre/tdTomato Mice
por: Voglsanger, Lara M., et al.
Publicado: (2021)

Familial bilateral cryptorchidism is caused by recessive variants in RXFP2
por: Ayers, Katie, et al.
Publicado: (2019)

Synthetic Covalently Linked Dimeric Form of H2 Relaxin Retains Native RXFP1 Activity and Has Improved In Vitro Serum Stability
por: Nair, Vinojini B., et al.
Publicado: (2015)

ODP010 Relaxin Receptor RXFP1 Knockout in Adipose Tissue Progenitor Cells Results in Resistance to High Fat Diet-Induced Weigh Gain
por: Bennett, Robert, et al.
Publicado: (2022)

In Vitro Pharmacological Characterization of RXFP3 Allosterism: An Example of Probe Dependency
por: Alvarez-Jaimes, Lily, et al.
Publicado: (2012)

Septal GABA and Glutamate Neurons Express RXFP3 mRNA and Depletion of Septal RXFP3 Impaired Spatial Search Strategy and Long-Term Reference Memory in Adult Mice
por: Haidar, Mouna, et al.
Publicado: (2019)

C1q/TNF-Related Proteins 1, 6 and 8 Are Involved in Corneal Epithelial Wound Closure by Targeting Relaxin Receptor RXFP1 In Vitro
por: Nicolaus, Hagen Fabian, et al.
Publicado: (2023)

Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin
por: Fernando, Shalinda J.A., et al.
Publicado: (2023)

The Fate of Spermatogonial Stem Cells in the Cryptorchid Testes of RXFP2 Deficient Mice
por: Ferguson, Lydia, et al.
Publicado: (2013)

Engineering of chimeric peptides as antagonists for the G protein-coupled receptor, RXFP4
por: Praveen, Praveen, et al.
Publicado: (2019)

Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex
por: Halls, Michelle L, et al.
Publicado: (2010)

The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
por: van Gastel, Jaana, et al.
Publicado: (2019)

Relaxin Signals through a RXFP1-pERK-nNOS-NO-cGMP-Dependent Pathway to Up-Regulate Matrix Metalloproteinases: The Additional Involvement of iNOS
por: Chow, Bryna Suet Man, et al.
Publicado: (2012)

A 1.8‐kb insertion in the 3′‐UTR of RXFP2 is associated with polledness in sheep
por: Wiedemar, Natalie, et al.
Publicado: (2015)

Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1
por: Wilhelmi, Tim, et al.
Publicado: (2020)

High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist
por: Lin, Guangyao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hdeu7bgpk0g7bqebnbtnbs1upb